Research Associate, Molecular & Cellular Immunology
Stylus Medicine · Cambridge, Massachusetts, United States
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- Location
- Cambridge, Massachusetts, United States
- Posted
About Stylus Medicine:
Stylus Medicine is developing transformative _in vivo_ genetic medicines to unlock cures. Stylus combines engineered recombinases with non-viral delivery to specifically encode therapeutics. The company’s approach is versatile and modular, with potential therapeutic application across oncology, autoimmune, genetic diseases, and beyond.
About the Role:
Stylus Medicine is seeking a highly motivated and collaborative Research Associate**** to join the Molecular and Cellular Immunology team. In this role, the Research Associate will assist in generating nucleic acid materials and performing _in vitro_ cell experiments, supporting the advancement of genetic medicines that leverage engineered recombinases delivered through non-viral methods. Working closely with cross-functional teams, this is a unique opportunity to work on the front lines of innovation and contribute to the advancement of transformational therapies.
Key Responsibilities & Accountabilities:
- Perform _in vitro_ T cell experiments to evaluate efficiency of recombinase-based engineering strategies and characterize the functional ability of resulting CAR-T cells
- Perform cloning and prepare nucleic acid and/or LNPs to support cell culture experiments
- Analyze and interpret data and produce data reports to inform project direction
- Effectively communicate findings to internal teams
- Maintain detailed and accurate laboratory records in compliance with data integrity and documentation standards
Qualifications & Skills:
- Bachelor’s degree in Biology, Bioengineering, Immunology, or a related field
- Hands-on molecular biology experience, including PCR, cloning, bacterial transformations, minipreps, maxipreps, and _in vitro_ transcription
- Hands-on mammalian cell culture expertise, including culturing tumor cell lines and primary T cells/PBMCs, co-culture experiments, flow cytometry, and genomic DNA extraction
- Familiarity producing targeted LNPs and/or working with CAR-T cells is preferred
- Demonstrated ability to execute, interpret, and troubleshoot experiments, both independently and collaboratively
- Experience maintaining meticulous records, including documenting and maintaining an organized lab notebook, lab inventory, and experimental results
- Excellent communication skills, with a team-first mindset and the ability to convey technical information
- Highly collaborative working style and ability to adapt in a fast paced, rapidly developing environment
- Enthusiasm and curiosity to learn and apply new lab techniques across a variety of sub-disciplines
Pay Range: $85,000-$95,000
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