Senior Research Associate, Antibody Discovery

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Bothell, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.

We are seeking a highly skilled and motivated Senior Research Associate to join our Antibody Discovery Group. The successful candidate will play a critical role in supporting the discovery of novel antibodies for therapeutic development. This is a laboratory-based role that utilizes various techniques, including BCR amplification, sequence analysis, and recombinant antibody expression. This position offers an exciting opportunity to work in a dynamic and innovative environment focused on the development of novel therapeutic antibodies.

_This is a full-time onsite position in Bothell, WA. _

Key Responsibilities:

• Amplify BCR sequences from sorted B-cells.
• Select antibody candidates through BCR sequence analysis.
• Design, clone, and express recombinant monoclonal antibodies.
• Prepare detailed reports and presentations.
• Maintain accurate records, ensure safety compliance, and contribute to lab organization.

Required Skills & Qualifications:

• Bachelor or master's degree in Immunology, Molecular Biology, Biochemistry, or a related field.
• Senior Research Associate requires bachelor's degree with 5+ years or master's degree with 3+ years of industry experience.
• 3+ years of hands-on experience in recombinant antibody expression.
• Strong molecular biology background and experience.
• Knowledge of antibody structure, humanization, production, and purification is preferred.
• Hands-on experience in NGS library preparation and BCR repertoire analysis is a plus.
• Experience in antibody discovery and development is highly desirable.

Technical Skills:

• Highly proficient in molecular biology techniques, including PCR (general, nested, etc.), cloning, plasmid DNA isolation, RNA isolation, and sequencing.
• Experience in eukaryotic cell transfection and culture.
• Hands-on experience in humanization of antibodies using various methods.
• Familiarity with sequence data analysis software and statistical tools (Geneious, Discovery Studio).

Soft Skills:

• Effective communication skills, both written and verbal.
• Strong organizational and time management skills.
• Excellent problem-solving and troubleshooting abilities.
• Ability to work independently and as part of a team.

Compensation and Benefits:

The expected base salary range for this position is $70,000 - $90,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate's level qualifications, experience, and skills.

While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.

_SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company's success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE. _

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_We offer an opportunity for you to learn and grow while making significant contributions to the company 's success. _

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_SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply. _